Surgery Resources

Transplantaton meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities. This is a title in the Companion to Specialist Surgical Practice series whose eight volumes are an established and highly regarded source of information for the specialist general surgeon. The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within each major surgical sub-specialty. Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter. Purchase of a print book also includes a downloadable version of the eBook. This new Fourth Edition is presented in colour throughout, including colour photographs of operative procedures, investigations and clinical signs throughout. The entire contents have been comprehensively updated with particular reference to the evidence-based content of each chapter. An expanded group of authors provides an increased international dimension to the content of all volumes. Purchase of a print copy includes a downloadable version of the eBook which you can also access on your iPhone, iPod Touch or iPad. In addition the books are available for purchase as a single volume or as part of a set of all eight volumes in an elegant slipcase. Fully updated to reflect the multidisciplinary team approach to transplant medicine.

Kidney Transplantation, Bioengineering, and Regeneration: Kidney Transplantation in the Regenerative Medicine Era investigates how the field of regenerative medicine is changing the traditional premises of solid organ transplantation, specifically within the field of kidney transplantation. In Section 1, chapters illustrate the state of the art in kidney transplantation as well as the research behind the bioengineering and regeneration of kidney organoids for therapeutic renal replacement. In Section II, chapters catalog the technologies that are being developed and the methods that are being implemented to bioengineer or regenerate kidneys in order to restore function, while critically highlighting those technological advances which hold the most promise. The book thus encompasses clinical renal transplantation, tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, as they are all applied to the kidney. Focuses on the synergy between renal organ transplantation and regenerative medicine, highlighting the advances within transplantation, bioengineering, regeneration, and repair Educates the transplant community on important regenerative medicine research pertinent to kidney transplantation Develops a shared language for clinicians, surgeons, and basic researchers to reach across the fields of transplantation and regenerative medicine, and facilitate more productive investigation and research Catalogs the technologies being developed and methods being implemented to bioengineer or regenerate kidneys to restore function

Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, in both adults and children. Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression. Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field. Includes new information on desensitization and considerable new data on the clinical use of costimulation blockade. Keeps you current with new chapters on kidney allocation policy that reflects the ethical and societal values of different countries and populations; and biomarkers of kidney injury and rejection, including the need for better monitoring tools to guide therapy and patient management. Covers hot topics such as management of chronic allograft failure, the sensitized patient and antibody-mediated rejection, and paired exchange principles. Features hundreds of superb illustrations to help you visualize key concepts and nuances of renal transplantation. Provides dynamic visual guidance with new real-time video coverage of ultrasound-guided pancreas allograft biopsy; a new animation of calcineurin inhibitor mechanism of action animation; and videos that demonstrate the formation of an immune synapse, 3-D rotational images of immune synapses, an NK cell killing its target, peritoneal dialysis-catheter insertion techniques, laparoendoscopic single site (LESS) donor nephrectomy, and more. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. "They have, in fact, succeeded in raising the bar yet again and making their work product even better in the third edition of Transplantation of the Liver." Forwords by, Thomas E. Starzl, June 2015 Access valuable pearls, pitfalls, and insights from Dr. Ronald Busuttil and Dr. Goran Klintmalm, two of the world's preeminent experts in liver surgery. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues. Overcome your toughest challenges in liver transplantation. Many new and thoroughly revised chapters include: Deceased Organ Donation after Cardiac and Brain Death; Liver Transplantation for Non-Alcoholic Steatohepatitis; Extended Criteria Donors; Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation; Small for Size Syndrome; Dual Grafts for Transplantation; Arterial Reconstructions-Pitfalls; Transition of Pediatric Patients to Adulthood; Immunosuppressive Biologic Agents; Long Term Toxicity of Immunosuppressive Therapy; Stem Cell and Liver Regeneration; and Extracorporeal Perfusion for Resuscitation of Marginal Grafts. Stay current in your field and optimize patient outcomes with coverage of the most recent advances in living donor transplantation, pediatric transplantation, and gene and stem cell therapy. Access the latest information on anti-rejection/immunosuppressive drugs, as well as comprehensive discussions of each drug or combination of drugs used to suppress immune system. Effortlessly search the entire text online at Expert Consult. With 104 additional contributing experts

The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the publica (TM)s trust in the process of organ donation and transplantation.

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